Buy Tolterodine utan recept

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Aktiv beståndsdel: Tolterodine
Varumärken): Detrol

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What is Tolterodine

Tolterodine is a aggressive cholinergic receptor antagonist with selectivity for the bladder. It will increase bladder capability, delays the primary urge to urinate and reduces micturition frequency in hyperactive bladder.

Tolterodine Drug Recommendation

For urgency incontinence, bladder retraining is the primary alternative. If insufficiently efficient, assist therapy with a controlled-release oral anticholinergic and/or once-daily dosage (darifenacin, fesoterodine, tolterodine, solifenacin). Commonly focus on whether or not the optimistic impact achieved outweighs the uncomfortable side effects:

  • torr mun
  • förstoppning
  • imaginative
  • prescient issues
  • cognitive problems

Indikationer

  • Symptomatic therapy of elevated urgency
  • frequent micturition and/or urgency incontinence
  • overactive bladder syndrome

Vad ska du diskutera med din läkare innan du använder detta läkemedel

  1. Att vara gravid
    • Teratogenesis: In people, inadequate knowledge. Indications of harmfulness in animals.
  2. Laktation
    • Övergång i bröstmjölk: Okänd.
  3.  Kontraindikationer
      • urinary retention;
      • extreme ulcerative colitis, poisonous megacolon;
      • myasthenia gravis;
      • inadequately regulated narrow-angle glaucoma.

Tolterodine Drug Interactions

Notably in case of ‘poor metabolizers’ watch out when combining with robust CYP3A4 inhibitors:

  • erytromycin
  • klaritromycin
  • ketokonazol
  • itrakonazol
  • miconazole
  • HIV-proteashämmare

Additionally watch out when combining with medicines that extend the QT interval

  • kinidin
  • disopyramid
  • sotalol
  • tricykliska antidepressiva medel
  • vissa antipsykotika
  • makrolidantibiotika
  • fluorokinoloner
  • vissa antimykotika

Anticholinergic results could also be added when used along with different brokers which have a parasympathetic impact. Tolterodine reduces the impact of brokers that promote gastrointestinal motility. The impact of tolterodine is decreased by parasympathicomimetics.

Tolterodine Dosage

Regardless of variations in pharmacokinetics between ‘ultra-rapid’ and ‘poor metabolisers’ (CYP2D6), the scientific response to the identical dose of tolterodine is comparable in each varieties of sufferers.

  • Elevated urgency, frequent micturition and/or urgency incontinence
    • Vuxna
      • Really helpful dose: 2 mg 2×/day or 4 mg managed launch capsule (mga) 1×/day. In case of troublesome uncomfortable side effects: 1 mg 2×/day or 2 mg capsule mga 1×/day. After 2-3 months, consider the necessity for additional therapy.
      • In case of impaired hepatic or extreme renal operate (≤ 30 ml/min): 1 mg 2×/day or 2 mg capsule mga 1×/day.
    • Administration: swallow the capsule complete.

Tecken på överdosering

  • Relying on severity:
    • lodging problems
    • miktionsproblem
    • takykardi
    • andningsinsufficiens
    • central anticholinergic results
      • extreme pleasure
      • hallucinationer
    • kramper

Remedy: If nonetheless helpful, gastric lavage and administration of activated charcoal. Deal with tachycardia with a β-blocker, urinary retention with catheterisation, pronounced agitation or convulsion with a benzodiazepine and extreme central anticholinergic results with physostigmine.

Tolterodine Precautions

Use warning with: important obstruction of the urinary or gastrointestinal tract; additionally with:

  • autonomic neuropathy
  • hiatus hernia
  • renal or hepatic insufficiency

Additionally watch out with threat elements for QT prolongation equivalent to:

  • bradykardi
  • hypokalemi
  • hypokalcemi
  • hypomagnesemi
  • comedication with medicine that extend QT interval
  • medfödd eller förvärvad QT-förlängning
  • current cardiac ailments equivalent to:
    • arytmi
    • myocardial ischaemia
    • kranskärlssvikt

The efficacy of tolterodine in youngsters has not been demonstrated. This drugs might have an effect on the flexibility to drive and use machines. 

Detrol Side Effects

  • torr mun
  • Huvudvärk
  • hjärtklappning
  • Dizziness, paraesthesia, drowsiness, fatigue
  • Dry pores and skin
  • Dry eyes, imaginative and prescient impairment, lodging issues
  • Dyspepsia, vomiting, stomach ache, constipation, diarrhoea, flatulence
  • Dysuria, urinary retention
  • Sinusitis, bronchitis
  • Peripheral oedema
  • Viktförvärv
  • Bröstvärk
  • takykardi
  • arytmi
  • kranskärlssvikt
  • Nervousness, reminiscence loss, improve in dementia
  • Gastro-oesophageal reflux
  • Överkänslighet

The next have additionally been reported: anaphylactic reactions together with angioedema. Flushing (extreme). Confusion, hallucinations, disorientation. When utilizing the controlled-release capsule, some uncomfortable side effects happen at a decrease frequency.

varning

Information concerning psychotic disorders, included within the review of Tolterodine, is used for the informative features exclusively as well as should not be thought-about to alternative to licensed healthcare or referral of the well being treatment distributor.

 

Ansvarsfriskrivning

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På denna webbplats säljer vi inga mediciner och hänvisar besökare till betrodda internetleverantörer. På detta sätt sparar vi dig och det bästa priset för människor många problem och du kan enkelt och lagligt få denna kraftfulla medicin.


Vanliga frågor

  • What is Tolterodine Detrol?

    Detrol contains tolterodine tartrate, the substance of cholinergic (acetyl-choline) receptor blockers class. The medication is used to reduce spasms of the bladder muscles, overactive bladder with symptoms of urge urinary incontinence, and frequency.

  • Vad ska du göra om du saknar en dos?

    If you miss a dose of Tolterodine, take it as quickly as potential. However, whether it is virtually time to your subsequent dose, skip the missed dose and return to your common dosing schedule. Do not double doses.

  • Vad händer om du tar för mycket Zanaflex?

    Om en överdosering inträffar, namnge din läkare eller ring ditt närmaste sjukhus. Du kan ha akut medicinsk vård. Du kan också kontakta gifthanteringen på ditt lokala sjukhus.

  • How to store Tolterodine?

    Förvara i rumstemperatur 15-30 C (59-86 F) borta från fukt och värme.

  • What Should I Avoid While Taking Tolterodine?

    Avoid consuming alcohol or utilizing unlawful medicine when you are taking Detrol. They might lower the advantages (e.g. worsen your confusion) and improve hostile results (e.g. sedation) of the remedy.

  • What are the side effects of Tolterodine Detrol?

    The most common side effects includes chest pain, fast or uneven heart rate, confusion, painful or difficult urination, hallucinations, urinating less than usual or not at all.


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Senast uppdaterad den 19 november 2021 av Toni El Clikos

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