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What is Risperidone or Risperdal

Risperidone belongs to the group of atypical antipsychotics. It reduces in the brain the effect of naturally occurring substances, mainly dopamine and serotonin. This decreases psychosis, severe agitation and certain muscle twitching. Doctors prescribe it for psychosis, mania, agitation, schizophrenia, depression, dementia, tics and obsessive-compulsive disorders.

  • In case of anxiety as a result of stress at work, this drug could be used, although it is a very strong active agent and if one has never been treated for this is not really a 1st choice. In that case, the short-term use of benzodiazepines is preferable.
  • It is used for people with dementia, mentally handicapped people and people with autism, as they can be very restless, aggressive or anxious. Risperidone reduces these symptoms within a few days. The duration of action of one dose is 12 to 24 hours. (HK)

Usage of Risperidone

Risperidone belongs to the atypical antipsychotics. This medication is used to treat schizophrenia and bipolar disorder as well as irritability associated with autistic disorder in children and adolescents aged 5-16 years. It can be also applied in other cases.

Dosage and direction

Take Risperdal by mouth with a glass of water, with or without food. Avoid cutting, crushing or chewing this medicine. Do not take the medicine more often than it is prescribed. Do not give up taking it except on the advice of your doctor. It may need time for medicine to help. Consult your doctor concerning the proper dose for you.


Before taking Risperidone to tell your doctor or chemist if you are allergic to it; or if you have other allergies. Inform your doctor or chemist if you have Parkinson’s disease, eye, liver or kidney problems, etc. Avoid drinking alcohol and smoking while being treated with this medication. Aged people can be more sensitive to the side effects of the medicine. During the pregnancy, this treatment should be used only when strongly necessary. As this medicament can be absorbed by skin, women who are pregnant or may become pregnant should not manipulate this medicine.


Risperdal should not be used by pregnant/nursing women or children as well as by the patients having demonstrated a reaction of hypersensitivity to Risperidone.

How to use Risperdal?

  • Utilized tablets: take with half a glass of water.
  • Drink: to measure out the correct amount, use the dosing pipette or a measuring cup or measuring spoon.
  • Melt tablets (‘orodisp’): first let them melt in the mouth and then swallow.
  • Injections: these will be administered into a gluteal muscle by the doctor or nurse. Usually this is once every 2 weeks.

How long do you use Risperdal?


If the psychotic episode is over, you will usually need to continue taking this medication for a long time. Otherwise, there is a high risk of another psychosis (relapse). The doctor will usually reduce the dosage during this period.

If you have had a psychosis for the first time, you usually have to continue taking this medicine for 1 or 2 years after your recovery, before you can try to stop. Only in exceptional cases, if you have recovered very quickly, can you try to stop six months after recovery. This must be done under proper supervision and the risk of relapse is still greater.Have you had a psychosis before, then you usually have to continue taking an antipsychotic for the rest of your life.


If the worst agitated symptoms have subsided, the doctor may recommend slowly tapering the use of risperidone. Lithium or valproïne acid should then usually continue to be used. Sometimes the doctor recommends continuing risperidone to prevent another mania.


Risperidone is usually used for several years by people with severe agitation, aggression, or anxiety. The dosage is usually reduced though as symptoms subside.


It is usually used for no longer than 6 weeks in dementia.

Tics and obsessive-compulsive disorder

If the drug works well, you usually have to keep taking it for several years.

Posttraumatic Stress Disorder

If the medicine is not having an effect after 3 months, it is probably not helpful to continue it. Talk to your doctor about this. After the symptoms improve, you should usually continue to use it for at least a year.

Side effects

The most common side effects are dry mouth, dizziness, irritability, sedation, insomnia, urinary retention, etc. A very serious allergic reaction rarely occurs. Many people using this medicine do not have serious side effects. Turn to your doctor or pharmacist for more details. In case you notice the effects not listed here, contact your doctor or pharmacist.

Missed dose

If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take your dose twice.


If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.


Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store your drugs in the bathroom. Keep all drugs away from reach of children and pets.

Disclaimer of liability

Pfizer is not affiliated with this site. The brand name and logos and images used are the property of Pfizer. The content of this site is for informational purposes only. We do not supply, market or ship medicines ourselves and refer you to reputable web stores on the Internet. Always consult a physician when using medicines.

On this website we do not sell any medications and refer visitors to trusted Internet providers. In this way, we save you and the best price to people many problems and you can easily and legally obtain this powerful medicine.

Frequently asked questions

What is Risperidone?

Risperidone belongs to the atypical antipsychotics. It reduces in the brain the effects of naturally occurring substances, mainly dopamine. This reduces psychosis and agitation. Doctors prescribe it for psychosis, mania, schizophrenia, agitation, dementia, tics in Tourette’s disease, obsessive-compulsive disorder and post-traumatic stress disorder. Look at all the different types of Risperidone here.

What should i do if i miss a dose?

It is important to take this medicine consistently. If you do forget a dose:

– If you are taking this medicine once a day: will it be more than 8 hours before you take the next dose as normal? Then take the forgotten dose. Will it be less than 8 hours? Then skip the forgotten dose.
– If you are taking this medicine twice a day: will it be more than 4 hours before you take the next dose as normal? If so, take the forgotten dose. Will it be less than 4 hours? Then skip the forgotten dose.
– Do you receive this medicine once every 2 weeks and did you forget the appointment? Make a new appointment immediately.

Can i just stop taking Risperdal?

Do not stop taking this medication lightly: many people develop another psychosis after stopping an antipsychotic drug. It is therefore important to consult with your doctor beforehand. In some psychoses the risk of a new psychosis is not so great, in others it is.
If you are going to stop, taper off slowly over a period of at least four weeks.

If you phase out gradually, you are less likely to experience a new psychosis right away. It also prevents withdrawal symptoms, such as sweating, nausea, loss of appetite, diarrhea, anxiety, sleeplessness, restlessness, runny nose, muscle pain and strange sensations, such as jitters. Look at all the different types of Risperdal here.

Does Risperidone have any interactions with other drugs?

Concomitant use with antihistamines, antidepressants, sleep aids, analgesics, opiates, or alcohol increases the sedative effect.
Concomitant use with strong CYP2D6 inhibitors (such as paroxetine, fluoxetine, quinidine, bupropion, cinacalcet), moderate to strong CYP3A4-/P-glycoprotein inhibitors (such as some HIV protease inhibitors, some macrolide antibiotics, imidazole antimycotics, aprepitant, diltiazem, verapamil, grapefruit juice) and strong CYP3A4/P-glycoprotein inducers (such as rifampicin, carbamazepine, phenobarbital, phenytoin, and St. John’s wort) may increase (CYP inhibitors) or decrease (CYP inducers) plasma concentrations of risperidone; reevaluate risperidone dosage when starting and stopping concomitant use with these agents. Look at all the different types of Risperdal here.

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Last Updated on August 29, 2021 by Toni El Clikos

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