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What is Nexium?

Nexium is a specific inhibitor of a proton pump (PPIs) of the parietal cells of the mucous layer of the stomach. It is a form of Prilosec (Omeprazole). It is accumulated and transformed into an active form in the secretory tubules where it inhibits the secretion of hydrochloric acid. Nexium is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, promote healing of erosive esophagitis, eradication of Helicobacter pylori together with antibiotics, preventive therapy of ulcers after treatment with anti-inflammatory non-steroid medications.

How should I use Esomeprazole (as Mg-Salt-2-Water)?

Tablets: take the tablet without chewing. If you chew the tablet, the protective layer is broken. This causes the medicine to be released in the stomach instead of in the intestines. It is then broken down by the stomach acid and will not work as well. If you have trouble swallowing, you may let the tablet fall apart in half a glass of water. It will then disintegrate into small granules, all of which have a protective coating. Stir the liquid and drink it. Afterwards, rinse the glass with a little water and drink this to soak up the remaining granules.

Capsules:

Take the capsule without chewing. If you chew the capsule to pieces, the protective layer breaks. This causes the medicine to be released in the stomach instead of in the intestines. It is then broken down by the stomach acid and will not work as well. If you have trouble swallowing, you may open the capsule and put the contents (small grains) into a half glass. Stir the liquid and drink it. Then rinse the glass with a little water and drink this to drink the remaining granules.

Bag of grains (granules):

Sprinkle one bag of granules in half a glass of water. Use tap water or bottled water without carbonation (non-carbonated). The granules disintegrate into even smaller granules with a protective layer. Stir the liquid, let it stand for a while and then drink it.

Then rinse the glass with a little water and drink this also to drink the remaining granules. It is important that you take the granules without chewing. If you chew the pellets, the protective layer is broken. This causes the medicine to be released in the stomach instead of in the intestines. It is then broken down by the stomach acid and will not work as well. If you need to take two packets, use a full glass of water to break up the granules.

When should I take this medicine?

You may take the medicine at any time of the day. If you have to take the medicine continuously, it is best to choose fixed times, then you are less likely to forget a dose. If you take it once a day: preferably in the morning. If you take it twice a day: in the morning and in the evening.

How long can I take esomeprazole?

The duration of use depends on the symptoms you are taking this medicine for. A stomach or duodenal ulcer may heal in four to eight weeks. Sometimes the doctor prescribes the medicine for a long time to prevent a return of the ulcer.

If you are taking the medicine to prevent stomach problems caused by anti-inflammatory painkillers or adrenal hormones, you should continue as long as you are taking these medicines.

Dosage and directions

To treat GERD, 20 or 40 mg of Nexium is given once daily during 4-8 weeks. Treatment of conditions caused by H. pylori requires 40 mg of Nexium administered once daily in combination with amoxicillin and clarithromycin during 10 days. Take Nexium capsules one hour before a meal, do not chew or crush them, swallow them whole.

Precautions

Before to take Nexium notify your doctor if you have any liver or kidney diseases. If your condition requires treatment with Nexium and antibiotics follow all instructions of your doctor to achieve the best results. Do not stop taking this medication even if your symptoms improved as your illness may not be completely treated. If you are pregnant, plan to become pregnant or breastfeeding consults your physician about it before to take this medication.

Contraindications

In children younger than 12 y.o., hypersensitivity to Nexium or to any other benzimidazole medication such as mebendazole (Vermox) and albendazole (Albenza), and in patients treated with atazanavir. Possible side effect Together with signs of allergy like hives, swelling of throat and face, rash patients may experience headache, diarrhoea, nausea, abdominal pain, flatulence (gas), constipation, or dry mouth. Notify your doctor if you think that you took too much of this medication.

Drug interaction

Nexium increases blood levels of diazepam (Valium) by decreasing the elimination of diazepam in the liver. Nexium and other PPIs reduce the absorption and concentration in blood of ketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin). Co-administration of Nexium with Clarithromycin increaes area under the plasma concentration-time curve (AUC) of the first. Nexium may slow down the metabolism of such medications: citalopram, diazepam, clomipramine, phenytoin, imipramine. Consequently, their dose should be corrected.

Missed dose

If you missed a dose take it the soonest. If it is almost time of your next dose just skip it and return to your regular dosage schedule. Never double dose this medication to compensate for the missed dose.

Overdose

If overdose of Nexium was taken the following symptoms occur: confusion, headache, drowsiness, blurred vision, rapid heartbeat, nausea, xerostomia (dry mouth), sweating, flushing, shallow breathing or shortness of breath, tremor, coordination disorders, or seizure. If you suppose that took too much of the drug to inform your doctor about it as you may need immediate medical help.

Storage

Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.

Disclaimer of liability

Pfizer is not affiliated with this site. The brand name and logos and images used are the property of Pfizer. The content of this site is for informational purposes only. We do not supply, market or ship medicines ourselves and refer you to reputable web stores on the Internet. Always consult a physician when using medicines.

On this website we do not sell any medications and refer visitors to trusted Internet providers. In this way, we save you and the best price to people many problems and you can easily and legally obtain this powerful medicine.


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Last Updated on July 23, 2021 by

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