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What is modafinil?
Modafinil, also known by its brand name Provigil, is a drug used to improve vigilance in patientsën with excessive sleepiness. It is similar to armodafinil (Nuvigil). Like amphetamines, it promotes wakefulness by stimulating the brain.
Why is modafinil prescribed?
Modafinil is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness). Also, this drug can help people who work nights or shifts to stay awake during the hours. It is also used in conjunction with respirators or other treatments to prevent excessive sleepiness caused by obstructive sleep apnea (a sleep disorder in which the patient briefly stops breathing once or several times and therefore cannot sleep peacefully through the night).
How does modafinil work?
The exact mechanism of action of this drug is unknown. It may work by increasing the amount of dopamine (a chemical neurotransmitter that nerves use to communicate with each other) in the brain by decreasing the reuptake of dopamine into the nerves.
In what dosages is modafinil prescribed?
The dose of this medicine may be different for each patient. Follow your doctor’s instructions or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to.
- For narcolepsy or obstructive sleep apnea/hypopnea syndrome:
- Adults and teens 17 years and older-200 mg modafinil (mg) once a day, ‘in the morning. Your doctor may increase your dose if necessary.
- When working shifts or having a sleep disorder at work:
- Adults and teenagers 17 years of age and older-200 mg of modafinil (mg) one hour before you start work.
How should I take modafinil?
The recommended dose is 200 mg of modafinil once daily and it should not exceed 400 mg of modafinil per day. For the treatment of narcolepsy or obstructive sleep apnea, it is best to take this medicine ‘in the morning. People who suffer from excessive sleepiness due to night work and shift work are advised to take it one hour before work. This medication may be taken with or without food.
With which medications or supplements does modafinil interact?
This medicine may affect or increase the activity of enzymes in the liver that metabolize (eliminate) other medicines. This may reduce the effectiveness of certain drugs. It may also increase the toxicity of other medications you take. Medications that may be less effective when taken with modafinil include cyclosporine (Sandimmune), theophylline, and hormonal contraceptives such as estrogen and progesterone-containing drugs (e.g. Micronor, Ortho-Novum 1/50).
- In addition, it is advisable to consider alternative hormonal contraceptives or an additional non-medicated form of contraception during the and one month after treatment with this drug.
- Drugs that may exhibit increased efficacy or toxicity in combination with modafinil include warfarin (Coumadin), diazepam (Valium), propranolol (Inderal), imipramine (Tofranil), desipramine (Norpramine), phenytoïne (Dilantin), and mefenytoïne (Mesantoïne).
- Other drugs that may increase the effectiveness and/or toxicity of modafinil include carbamazepine (Tegretol), phenobarbital, and rifampin (Rifadin).
- Other drugs, such as ketoconazole (Nizoral) and itraconazole (Sporanox) may reduce the effectiveness of modafinil. Methylphenidate may slow the action of modafinil.
What precautions should I take regarding the use of modafinil?
Please inform your doctor or pharmacist of your medication use and any alergies. This product may contain inactive ingredients that can cause allergic reactions or other problems. It is also advisable to inform your healthcare provider of your medical history, especially if you suffer from any of the following conditions:
- Heart problems such as an enlarged heart, chest pain and/or an irregular heartbeat
- problemi al fegato
- Mental problems
- Previous substance use such as excessive use of or addiction to drugs/alcohol).
Sleep disorders may reduce your ability to react quickly. Although modafinil helps to keep you awake, you may still be unable to do acitivities that require a quick response such as driving. This medication may also make you dizzy. Do not drive, use machinery, or do anything that requires alertness until you know how this drug affects you.
Tell your doctor if you are pregnant or plan to become pregnant. During pregnancy, the use of this smart drug is not recommended. It may harm an unborn baby. Ask about reliable forms of non-hormonal contraception while using this medication and for 2 months after stopping treatment. If you become pregnant, talk to your doctor right away about the risks’s and benefits of this medication.
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What is Modalert (Modafinil) used for?
Modalert (Modafinil) is an oral medication prescribed to treat daytime sleepiness caused by narcolepsy or obstructive sleep apnoea. It operates by adjusting the balance of chemicals in the brain to promote wakefulness and alertness during the day. Your doctor may also prescribe its use for the treatment of other unlisted conditions.
How should I use Modalert (Modafinil)?
Strictly follow your doctor`s instructions while using Modalert (Modafinil) to get the safest and most effective results from treatment. One tablet is normally administered once daily in the morning. Your particular instructions will depend on your age, weight, health condition, and the severity of your symptoms. They should be swallowed with a large glass of water and may be taken on an empty stomach, although a snack or meal is suggested prior to use if you experience nausea. Do not split or crush the tablets before use to avoid destroying or altering the effects of their contents.
What are the side effects of Modalert (Modafinil)?
Modalert (Modafinil) may cause side effects in some patients such as:
- Mal di testa
- Bocca asciutta
Nausea or vomiting
- Upset stomach or diarrhoea
- Anxiety or nervousness
Serious side effects that may require emergency medical attention are sensitive skin, easier bruising, muscle pain, fever, flu symptoms, depression, severe anxiety, chest pain, irregular heartbeats, sores appearing in or around the mouth, or hallucinations. Tell your doctor about any worrying symptoms you experience to make sure the necessary adjustments are made to your dosage or application frequency to prevent further health complications from occurring.
- Do not begin using Modalert (Modafinil) if you are pregnant, breastfeeding, lactose intolerant, if you have arrhythmias, hypertension, a heart valve disorder, or a history of enlargement of a chamber in the heart. You are also suggested to inform your doctor if you have a history of mental illness, severe anxiety, hypertension, heart disease, a history of substance abuse, kidney failure, or liver failure. These conditions may cause unexpected health problems requiring special adjustments to your regimen. Strictly use Modalert (Modafinil) as prescribed and follow all instructions provided by your doctor. Safe, suitable, and optimum dosage can vary and is dependent on the patient`s health and medical history, as well as the condition you are treating.
- Modalert (Modafinil) may not be safe or suitable for all patients. Always ensure your doctor is informed if you are pregnant or breastfeeding, using any other type of medication (including non-prescription medicine, vitamins, and supplements), as well as if you have any allergies, other illnesses, or pre-existing medication conditions. Seek immediate medical attention or proceed to your nearest accident and emergency department if you suffer a hypersensitive or allergic reaction. Symptoms usually present during a reaction of this nature include difficulty breathing or swallowing, swelling of the limbs or face, tight chest, hives, and skin rashes.
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